Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors and other biologically active compounds. Its structure allows for selective functionalization, making it valuable in medicinal chemistry for constructing complex heterocyclic systems. Commonly employed in cross-coupling reactions, such as Suzuki and Buchwald–Hartwig aminations, to introduce the isonicotinonitrile scaffold into target molecules. Also utilized in agrochemical research for designing novel active ingredients due to its reactivity and stability profile.