Used in cancer research as a potent and selective inhibitor of the MDM2-p53 protein-protein interaction. By blocking MDM2, it stabilizes the tumor suppressor p53, leading to cell cycle arrest and apoptosis in cancer cells that overexpress MDM2. Shows promising activity in preclinical models of solid tumors and hematological malignancies, particularly those with wild-type p53. Investigated for its potential in targeted therapy where p53 function is intact but suppressed by high MDM2 levels.