5-(Methylthio)-1H-tetrazole
97 %
Reagent
Code: #206298
CAS Number
29515-99-9
blur_circular Chemical Specifications
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Molecular Information
Weight
116.14 g/mol
Formula
C₂H₄N₄S
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Registry Numbers
MDL Number
MFCD00068726
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Physical Properties
Melting Point
149-152°C (Lit.)
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, such as losartan, valsartan, and irbesartan, which are widely prescribed for hypertension and cardiovascular diseases. It serves as a bioisostere for carboxylic acid groups, improving metabolic stability and oral bioavailability in pharmaceutical compounds. Also employed in coordination chemistry as a ligand for metal ions due to its nitrogen-rich heterocyclic structure. Additionally, finds use in the development of energetic materials and corrosion inhibitors.
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5-(Methylthio)-1H-tetrazole
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, such as losartan, valsartan, and irbesartan, which are widely prescribed for hypertension and cardiovascular diseases. It serves as a bioisostere for carboxylic acid groups, improving metabolic stability and oral bioavailability in pharmaceutical compounds. Also employed in coordination chemistry as a ligand for metal ions due to its nitrogen-rich heterocyclic structure. Additionally, finds use in the development of energetic materials and corrosion inhibitors.
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