1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indolin-2-one
95%
Reagent
Code: #209081
CAS Number
1220696-38-7
blur_circular Chemical Specifications
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Molecular Information
Weight
273.14 g/mol
Formula
C₁₅H₂₀BNO₃
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Registry Numbers
MDL Number
MFCD18383773
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Storage & Handling
Storage
2-8°C, stored in inert gas
description Product Description
Used in organic synthesis as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds for constructing complex indolinone derivatives. Valuable in pharmaceutical research for developing kinase inhibitors and other bioactive molecules due to the indolinone scaffold's prevalence in drug-like compounds. The boronate ester group allows for efficient and selective coupling with aryl or heteroaryl halides under mild palladium catalysis. Commonly employed in medicinal chemistry for library synthesis and structure-activity relationship studies.
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1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indolin-2-one
Used in organic synthesis as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds for constructing complex indolinone derivatives. Valuable in pharmaceutical research for developing kinase inhibitors and other bioactive molecules due to the indolinone scaffold's prevalence in drug-like compounds. The boronate ester group allows for efficient and selective coupling with aryl or heteroaryl halides under mild palladium catalysis. Commonly employed in medicinal chemistry for library synthesis and structure-activity relationship studies.
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