4'-(Methylsulfonyl)-[1,1'-biphenyl]-2-carboxylic acid
≥95%
Reagent
Code: #209188
CAS Number
893736-90-8
blur_circular Chemical Specifications
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Molecular Information
Weight
276.31 g/mol
Formula
C₁₄H₁₂O₄S
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Registry Numbers
MDL Number
MFCD06802579
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Storage & Handling
Storage
Room temperature, dry seal
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of antihypertensive drugs like Valsartan and related sartan-class medications. Its structure enables effective binding to the angiotensin II receptor, helping to block vasoconstriction and regulate blood pressure. The methylsulfonyl and carboxylic acid functional groups enhance solubility and receptor interaction, making it valuable in pharmaceutical development for cardiovascular diseases. Also employed in research for designing new bioactive molecules due to its favorable pharmacokinetic properties and stability.
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4'-(Methylsulfonyl)-[1,1'-biphenyl]-2-carboxylic acid
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of antihypertensive drugs like Valsartan and related sartan-class medications. Its structure enables effective binding to the angiotensin II receptor, helping to block vasoconstriction and regulate blood pressure. The methylsulfonyl and carboxylic acid functional groups enhance solubility and receptor interaction, making it valuable in pharmaceutical development for cardiovascular diseases. Also employed in research for designing new bioactive molecules due to its favorable pharmacokinetic properties and stability.
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