N,N-Diethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine
98%
Reagent
Code: #219649
CAS Number
1218791-45-7
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Molecular Information
Weight
277.17 g/mol
Formula
C₁₄H₂₄BN₃O₂
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Registry Numbers
MDL Number
MFCD12546555
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Storage & Handling
Storage
Room temperature, inert gas
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boronate ester group readily participates in palladium-catalyzed coupling with aryl or heteroaryl halides, making it valuable for constructing complex nitrogen-containing heterocycles. Commonly employed in the development of bioactive molecules, particularly in medicinal chemistry for drug discovery and optimization. Stable and compatible with a variety of functional groups, it allows for efficient late-stage functionalization in synthetic routes.
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N,N-Diethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boronate ester group readily participates in palladium-catalyzed coupling with aryl or heteroaryl halides, making it valuable for constructing complex nitrogen-containing heterocycles. Commonly employed in the development of bioactive molecules, particularly in medicinal chemistry for drug discovery and optimization. Stable and compatible with a variety of functional groups, it allows for efficient late-stage functionalization in synthetic routes.
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