Used as a powerful reagent for the direct conversion of carboxylic acids into amides or peptides without the need for pre-activation. It enables efficient Beckmann rearrangement reactions, useful in the synthesis of lactams and other nitrogen-containing cyclic compounds. Commonly applied in pharmaceutical and fine chemical industries for constructing complex molecules, especially where mild reaction conditions and high selectivity are required. Also employed in the preparation of hydroxamic acids and other functionalized intermediates in organic synthesis.