Used as a potent and selective inhibitor in targeted cancer therapies, particularly effective against tumors driven by ALK (anaplastic lymphoma kinase) and ROS1 gene rearrangements. It is designed to penetrate the central nervous system, making it valuable in treating brain metastases commonly associated with non-small cell lung cancer. Its high selectivity helps reduce off-target effects, improving patient tolerance during treatment. Currently utilized in clinical research to evaluate long-term efficacy and safety in advanced-stage cancer patients.