Picropodophyllon

Analytical reference substance, ≥98% (HPLC)

Reagent Code: #227140
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CAS Number 477-48-5

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scatter_plot Molecular Information
Weight 412.39 g/mol
Formula C₂₂H₂₀O₈
thermostat Physical Properties
Melting Point 153-154 °C
Boiling Point 602.3±55.0 °C at 760 mmHg
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used in cancer research due to its ability to inhibit the insulin-like growth factor 1 receptor (IGF-1R), which plays a role in tumor cell proliferation and survival. Shows potential as an anti-cancer agent, particularly in studies involving glioblastoma, melanoma, and other solid tumors. Demonstrates cytotoxic effects on cancer cells while sparing normal cells, making it a candidate for targeted therapy development. Also used as a reference compound in biochemical assays studying kinase inhibition and apoptosis induction.

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Size Availability Unit Price Quantity
inventory 10mg
10-20 days ฿36,310.00
Picropodophyllon
Used in cancer research due to its ability to inhibit the insulin-like growth factor 1 receptor (IGF-1R), which plays a role in tumor cell proliferation and survival. Shows potential as an anti-cancer agent, particularly in studies involving glioblastoma, melanoma, and other solid tumors. Demonstrates cytotoxic effects on cancer cells while sparing normal cells, making it a candidate for targeted therapy development. Also used as a reference compound in biochemical assays studying kinase inhibition and apoptosis induction.
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