Ro 61-8048
10mM in DMSO
Reagent
Code: #229684
CAS Number
199666-03-0
blur_circular Chemical Specifications
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Molecular Information
Weight
421.45 g/mol
Formula
C₁₇H₁₅N₃O₆S₂
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily in scientific research to study the kynurenine pathway, particularly as a potent and selective inhibitor of kynurenine 3-monooxygenase (KMO). This inhibition shifts the metabolism of kynurenine toward kynurenic acid production, which has neuroprotective properties due to its ability to block glutamate receptors and reduce excitotoxicity. As a result, it is investigated for potential therapeutic applications in neurodegenerative diseases such as Huntington’s disease, Alzheimer’s disease, and Parkinson’s disease. It has also been used to explore the role of neuroinflammation and immune modulation in psychiatric disorders like schizophrenia and depression. Its ability to cross the blood-brain barrier makes it a valuable tool in central nervous system research.
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Ro 61-8048
Used primarily in scientific research to study the kynurenine pathway, particularly as a potent and selective inhibitor of kynurenine 3-monooxygenase (KMO). This inhibition shifts the metabolism of kynurenine toward kynurenic acid production, which has neuroprotective properties due to its ability to block glutamate receptors and reduce excitotoxicity. As a result, it is investigated for potential therapeutic applications in neurodegenerative diseases such as Huntington’s disease, Alzheimer’s disease, and Parkinson’s disease. It has also been used to explore the role of neuroinflammation and immune modulation in psychiatric disorders like schizophrenia and depression. Its ability to cross the blood-brain barrier makes it a valuable tool in central nervous system research.
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