Ro 61-8048

10mM in DMSO

Reagent Code: #229684
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CAS Number 199666-03-0

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Weight 421.45 g/mol
Formula C₁₇H₁₅N₃O₆S₂
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used primarily in scientific research to study the kynurenine pathway, particularly as a potent and selective inhibitor of kynurenine 3-monooxygenase (KMO). This inhibition shifts the metabolism of kynurenine toward kynurenic acid production, which has neuroprotective properties due to its ability to block glutamate receptors and reduce excitotoxicity. As a result, it is investigated for potential therapeutic applications in neurodegenerative diseases such as Huntington’s disease, Alzheimer’s disease, and Parkinson’s disease. It has also been used to explore the role of neuroinflammation and immune modulation in psychiatric disorders like schizophrenia and depression. Its ability to cross the blood-brain barrier makes it a valuable tool in central nervous system research.

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Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿7,420.00
Ro 61-8048
Used primarily in scientific research to study the kynurenine pathway, particularly as a potent and selective inhibitor of kynurenine 3-monooxygenase (KMO). This inhibition shifts the metabolism of kynurenine toward kynurenic acid production, which has neuroprotective properties due to its ability to block glutamate receptors and reduce excitotoxicity. As a result, it is investigated for potential therapeutic applications in neurodegenerative diseases such as Huntington’s disease, Alzheimer’s disease, and Parkinson’s disease. It has also been used to explore the role of neuroinflammation and immune modulation in psychiatric disorders like schizophrenia and depression. Its ability to cross the blood-brain barrier makes it a valuable tool in central nervous system research.
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