Used in research to study cell death pathways, particularly in necroptosis and inflammation-related diseases. Shows potential in treating neurodegenerative conditions like Alzheimer's and Parkinson's by blocking RIP1 kinase activity. Investigated for autoimmune disorders due to its role in modulating immune responses. Also explored in cancer therapy to enhance the effectiveness of other treatments by promoting tumor cell death. Not approved for clinical use; primarily a tool compound in preclinical studies.