Used primarily as a reference standard or impurity marker in the quality control of pharmaceutical formulations containing linagliptin, this compound plays a critical role in analytical testing. It helps in identifying and quantifying impurities during the manufacturing process, ensuring drug purity and regulatory compliance. Its presence is monitored in stability studies to assess degradation pathways of linagliptin under various conditions such as heat, light, or humidity. Additionally, it supports method development and validation of analytical techniques like HPLC and LC-MS for accurate detection of related substances in active pharmaceutical ingredients.