Used in the treatment of schizophrenia, sertindole helps manage symptoms such as hallucinations, delusions, and disorganized thinking. It works by affecting certain neurotransmitters in the brain, primarily dopamine and serotonin. Due to its action on these systems, it can help stabilize mood and improve cognitive function in patients with psychotic disorders. It may also be used off-label for other psychiatric conditions, though its use requires careful monitoring because of potential cardiac side effects.