Used as a chiral building block in the synthesis of pharmaceuticals, particularly in the development of active pharmaceutical ingredients (APIs) where stereochemistry plays a critical role in biological activity. Its rigid piperazine backbone with defined stereocenters makes it valuable in medicinal chemistry for designing drugs with improved selectivity and metabolic stability. Commonly employed in the preparation of kinase inhibitors and central nervous system (CNS) agents. Also utilized in asymmetric synthesis and as a ligand precursor in catalytic reactions.