7-(Trimethylsilyl)hept-6-ynoic acid
97%
Reagent
Code: #238591
CAS Number
473542-74-4
blur_circular Chemical Specifications
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Molecular Information
Weight
198.3342 g/mol
Formula
C₁₀H₁₈O₂Si
thermostat
Physical Properties
Boiling Point
267.1±23.0 °C(Predicted)
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Storage & Handling
Density
0.956±0.06 g/cm3(Predicted)
Storage
2-8°C
description Product Description
Used primarily as a key intermediate in organic synthesis, especially in pharmaceutical and agrochemical research. Its alkyne functionality allows for click chemistry applications, such as copper-catalyzed azide-alkyne cycloaddition (CuAAC), enabling efficient conjugation in complex molecule assembly. The trimethylsilyl group stabilizes the alkyne and enhances reactivity in Sonogashira coupling reactions. It is also employed in the preparation of functionalized fatty acid analogs and bioactive molecule derivatization where controlled lipophilicity and steric bulk are required. Its carboxylic acid group facilitates amide bond formation, making it useful in peptide-like scaffold construction.
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7-(Trimethylsilyl)hept-6-ynoic acid
Used primarily as a key intermediate in organic synthesis, especially in pharmaceutical and agrochemical research. Its alkyne functionality allows for click chemistry applications, such as copper-catalyzed azide-alkyne cycloaddition (CuAAC), enabling efficient conjugation in complex molecule assembly. The trimethylsilyl group stabilizes the alkyne and enhances reactivity in Sonogashira coupling reactions. It is also employed in the preparation of functionalized fatty acid analogs and bioactive molecule derivatization where controlled lipophilicity and steric bulk are required. Its carboxylic acid group facilitates amide bond formation, making it useful in peptide-like scaffold construction.
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