2-(2,2,2-Trifluoroethoxy)pyrimidine-5-carboxylic acid
97%
- Product Code: 241738
CAS:
944905-08-2
| Molecular Weight: | 222.12 g./mol | Molecular Formula: | C₇H₅F₃N₂O₃ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD10696903 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | Room temperature, dry seal |
Product Description:
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of kinase inhibitors and antiviral drugs. Its structure supports binding to enzyme active sites, enhancing biological activity. The trifluoroethoxy group improves metabolic stability and lipophilicity, making it valuable in optimizing drug candidates for better oral bioavailability and target selectivity. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies to refine potency and pharmacokinetic properties.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | $805.63 |
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| 0.250 | 10-20 days | $1,611.27 |
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2-(2,2,2-Trifluoroethoxy)pyrimidine-5-carboxylic acid
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of kinase inhibitors and antiviral drugs. Its structure supports binding to enzyme active sites, enhancing biological activity. The trifluoroethoxy group improves metabolic stability and lipophilicity, making it valuable in optimizing drug candidates for better oral bioavailability and target selectivity. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies to refine potency and pharmacokinetic properties.
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