2-(Trifluoromethoxy)pyridin-4-amine
97%
Reagent
Code: #243231
CAS Number
1221172-01-5
blur_circular Chemical Specifications
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Molecular Information
Weight
178.11 g/mol
Formula
C₆H₅F₃N₂O
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Registry Numbers
MDL Number
MFCD19690147
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Physical Properties
Boiling Point
215.1±35.0 °C at 760 mmHg
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Storage & Handling
Storage
2-8°C, avoiding light
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of agrochemicals and bioactive molecules. Its structure supports the creation of compounds with enhanced metabolic stability and binding affinity. Commonly employed in the manufacture of herbicides and fungicides due to the electron-withdrawing trifluoromethoxy group improving lipophilicity and environmental persistence. Also utilized in medicinal chemistry for designing kinase inhibitors and CNS-active agents where the pyridine core and fluorinated substituent contribute to improved blood-brain barrier penetration and target selectivity.
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2-(Trifluoromethoxy)pyridin-4-amine
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of agrochemicals and bioactive molecules. Its structure supports the creation of compounds with enhanced metabolic stability and binding affinity. Commonly employed in the manufacture of herbicides and fungicides due to the electron-withdrawing trifluoromethoxy group improving lipophilicity and environmental persistence. Also utilized in medicinal chemistry for designing kinase inhibitors and CNS-active agents where the pyridine core and fluorinated substituent contribute to improved blood-brain barrier penetration and target selectivity.
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