2-((TERT-BUTOXYCARBONYL)AMINO)-2-(4,4-DIFLUOROCYCLOHEXYL)ACETIC ACID
95%
Reagent
Code: #244180
CAS Number
1822546-08-6
blur_circular Chemical Specifications
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Molecular Information
Weight
293.31 g/mol
Formula
C₁₃H₂₁F₂NO₄
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Registry Numbers
MDL Number
MFCD16250458
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Storage & Handling
Storage
2-8°C, sealed, dry
description Product Description
Used as an intermediate in the synthesis of biologically active compounds, particularly in pharmaceutical development. Its structure supports the construction of complex molecules where a protected amino group and a fluorinated cyclohexyl moiety are required. Commonly employed in peptide-like synthesis and in the preparation of protease inhibitors or receptor modulators. The Boc-protected amine allows for controlled deprotection under mild acidic conditions, enabling stepwise assembly in multi-step organic syntheses. The geminal difluoro substitution on the cyclohexyl ring enhances metabolic stability and membrane permeability in drug candidates, making this compound valuable in medicinal chemistry for optimizing pharmacokinetic properties.
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2-((TERT-BUTOXYCARBONYL)AMINO)-2-(4,4-DIFLUOROCYCLOHEXYL)ACETIC ACID
Used as an intermediate in the synthesis of biologically active compounds, particularly in pharmaceutical development. Its structure supports the construction of complex molecules where a protected amino group and a fluorinated cyclohexyl moiety are required. Commonly employed in peptide-like synthesis and in the preparation of protease inhibitors or receptor modulators. The Boc-protected amine allows for controlled deprotection under mild acidic conditions, enabling stepwise assembly in multi-step organic syntheses. The geminal difluoro substitution on the cyclohexyl ring enhances metabolic stability and membrane permeability in drug candidates, making this compound valuable in medicinal chemistry for optimizing pharmacokinetic properties.
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