5-(tert-butoxycarbonylamino)-2-(2,6-difluorophenyl)thiazole-4-carboxylic acid
≥95%
Reagent
Code: #244644
CAS Number
1270034-25-7
blur_circular Chemical Specifications
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Molecular Information
Weight
356.34 g/mol
Formula
C₁₅H₁₄F₂N₂O₄S
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Registry Numbers
MDL Number
MFCD21607185
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Storage & Handling
Storage
2-8°C, sealed, dry, light-proof
description Product Description
Used as a key intermediate in the synthesis of kinase inhibitors, particularly in the development of anticancer agents. Its structure allows for selective modification in drug design, making it valuable in creating compounds that target specific signaling pathways in tumor cells. Commonly employed in solid-phase and solution-phase peptide-like coupling reactions due to the presence of both carboxylic acid and protected amino functionalities. Also utilized in combinatorial chemistry for generating libraries of biologically active molecules. Its fluorinated aryl group enhances binding affinity and metabolic stability in final drug candidates.
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5-(tert-butoxycarbonylamino)-2-(2,6-difluorophenyl)thiazole-4-carboxylic acid
Used as a key intermediate in the synthesis of kinase inhibitors, particularly in the development of anticancer agents. Its structure allows for selective modification in drug design, making it valuable in creating compounds that target specific signaling pathways in tumor cells. Commonly employed in solid-phase and solution-phase peptide-like coupling reactions due to the presence of both carboxylic acid and protected amino functionalities. Also utilized in combinatorial chemistry for generating libraries of biologically active molecules. Its fluorinated aryl group enhances binding affinity and metabolic stability in final drug candidates.
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