2-(2-(3-(4-Methylpyridin-2-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)ethyl)isoindoline-1,3-dione

98%

Reagent Code: #245813
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CAS Number 381196-41-4

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 410.42 g/mol
Formula C₂₄H₁₈N₄O₃
thermostat Physical Properties
Boiling Point 649.1±65.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.37±0.1 g/cm3(Predicted)
Storage -20°C, Sealed, Dry

description Product Description

Used in pharmaceutical research as a key intermediate in the synthesis of kinase inhibitors, particularly targeting tyrosine kinases involved in cancer cell proliferation. Its structure supports binding to enzyme active sites, making it valuable in developing anticancer agents. Also employed in the design of targeted protein degraders like PROTACs, where it acts as a warhead component to induce degradation of disease-causing proteins. Commonly utilized in structure-activity relationship (SAR) studies to optimize potency and selectivity in drug candidates.

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Size Availability Unit Price Quantity
inventory 5mg
10-20 days $219.18
inventory 25mg
10-20 days $850.94
inventory 1mg
10-20 days $74.35
2-(2-(3-(4-Methylpyridin-2-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)ethyl)isoindoline-1,3-dione
Used in pharmaceutical research as a key intermediate in the synthesis of kinase inhibitors, particularly targeting tyrosine kinases involved in cancer cell proliferation. Its structure supports binding to enzyme active sites, making it valuable in developing anticancer agents. Also employed in the design of targeted protein degraders like PROTACs, where it acts as a warhead component to induce degradation of disease-causing proteins. Commonly utilized in structure-activity relationship (SAR) studies to optimize potency and selectivity in drug candidates.
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