2-(2-(3-(4-Methylpyridin-2-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)ethyl)isoindoline-1,3-dione
98%
Reagent
Code: #245813
CAS Number
381196-41-4
blur_circular Chemical Specifications
scatter_plot
Molecular Information
Weight
410.42 g/mol
Formula
C₂₄H₁₈N₄O₃
thermostat
Physical Properties
Boiling Point
649.1±65.0 °C(Predicted)
inventory_2
Storage & Handling
Density
1.37±0.1 g/cm3(Predicted)
Storage
-20°C, Sealed, Dry
description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of kinase inhibitors, particularly targeting tyrosine kinases involved in cancer cell proliferation. Its structure supports binding to enzyme active sites, making it valuable in developing anticancer agents. Also employed in the design of targeted protein degraders like PROTACs, where it acts as a warhead component to induce degradation of disease-causing proteins. Commonly utilized in structure-activity relationship (SAR) studies to optimize potency and selectivity in drug candidates.
shopping_cart Available Sizes & Pricing
2-(2-(3-(4-Methylpyridin-2-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)ethyl)isoindoline-1,3-dione
Used in pharmaceutical research as a key intermediate in the synthesis of kinase inhibitors, particularly targeting tyrosine kinases involved in cancer cell proliferation. Its structure supports binding to enzyme active sites, making it valuable in developing anticancer agents. Also employed in the design of targeted protein degraders like PROTACs, where it acts as a warhead component to induce degradation of disease-causing proteins. Commonly utilized in structure-activity relationship (SAR) studies to optimize potency and selectivity in drug candidates.
Mechanism | - |
Appearance | - |
Longevity | - |
Strength | - |
Storage | - |
Shelf Life | - |
Allergen(s) | - |
Dosage (Range) | - |
Recommended Dosage | - |
Dosage (Per Day) | - |
Recommended Dosage (Per Day) | - |
Mix Method | - |
Heat Resistance | - |
Stable in pH range | - |
Solubility | - |
Product Types | - |
INCI | - |
Purchase History for
Loading purchase history...
Cart
No products
Subtotal:
$0.00
Total
$0.00
CAD