(Z)-2-(2-Aminothiazol-4-yl)-2-(tert-Butoxycarbonylmethoxyimino)acetic acid

98%

Reagent Code: #246595
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CAS Number 74440-02-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 301.32 g/mol
Formula C₁₁H₁₅N₃O₅S
thermostat Physical Properties
Boiling Point 482.8°C
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used as a key intermediate in the synthesis of third-generation cephalosporin antibiotics, particularly in the production of ceftriaxone and similar beta-lactam antibiotics. Its structure allows for efficient coupling with other antibiotic moieties, enhancing antimicrobial activity and stability against beta-lactamase enzymes. Commonly employed in pharmaceutical manufacturing to introduce the aminothiazole oxime side chain, which improves penetration into bacterial cells and broadens the spectrum of activity against Gram-negative bacteria.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 1g
10-20 days $18.63
inventory 5g
10-20 days $65.20
(Z)-2-(2-Aminothiazol-4-yl)-2-(tert-Butoxycarbonylmethoxyimino)acetic acid
Used as a key intermediate in the synthesis of third-generation cephalosporin antibiotics, particularly in the production of ceftriaxone and similar beta-lactam antibiotics. Its structure allows for efficient coupling with other antibiotic moieties, enhancing antimicrobial activity and stability against beta-lactamase enzymes. Commonly employed in pharmaceutical manufacturing to introduce the aminothiazole oxime side chain, which improves penetration into bacterial cells and broadens the spectrum of activity against Gram-negative bacteria.
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