1-(3-Bromophenyl)-3-(2,2,2-trifluoroethyl)urea
95%
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description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of bioactive molecules targeting central nervous system disorders. Its structural features, including the 3-bromophenyl and 2,2,2-trifluoroethyl groups, enhance lipophilicity, enabling penetration of the blood-brain barrier, which is essential for CNS-acting drugs. This makes it valuable in medicinal chemistry for modulating receptor binding affinity, especially in serotonin and dopamine receptor ligands. Also employed in agrochemical research for designing novel pesticides with improved metabolic stability due to the presence of the trifluoroethyl group. Shows utility in creating urea-based inhibitors for enzymes involved in signal transduction pathways.
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