Buphenine HCl is primarily used as a vasodilator to improve blood flow in conditions involving peripheral vascular disorders. It is effective in treating symptoms associated with circulatory issues, such as intermittent claudication, Raynaud's disease, and other conditions where enhanced peripheral circulation is beneficial. Additionally, it has been utilized in managing certain types of headaches by promoting vascular relaxation. Its ability to reduce smooth muscle tension in blood vessels also makes it useful in alleviating symptoms of chronic venous insufficiency. In some cases, it is employed to support recovery in patients with frostbite or other cold-induced injuries by improving blood supply to affected areas.