Vericiguat is primarily used in the treatment of chronic heart failure, particularly in patients who have experienced a recent worsening of their condition. It works by stimulating the enzyme soluble guanylate cyclase (sGC), which plays a crucial role in regulating cardiovascular function. This stimulation helps to relax blood vessels, improve blood flow, and reduce the strain on the heart. By enhancing the signaling pathway of nitric oxide, vericiguat aids in managing symptoms and reducing the risk of hospitalization due to heart failure. It is often prescribed as part of a comprehensive treatment plan, alongside other medications and lifestyle modifications, to improve overall heart health and patient outcomes.