Angoline hydrochloride is primarily used in the field of medical research, particularly in studies related to cardiovascular diseases. It acts as a vasodilator, helping to widen blood vessels and improve blood flow, which is crucial in managing conditions like hypertension and angina. Additionally, it is utilized in pharmacological experiments to understand its effects on smooth muscle relaxation and its potential therapeutic benefits. Researchers also explore its role in reducing vascular resistance, which can be beneficial in treating heart failure and other circulatory disorders. Its application extends to preclinical trials for evaluating safety and efficacy in new drug formulations targeting cardiovascular health.