Used in veterinary research and diagnostic laboratories to measure levels of tissue inhibitor of metalloproteinase-1 (TIMP-1) in canine biological samples such as serum, plasma, or tissue homogenates. This assay helps assess the regulation of matrix metalloproteinases (MMPs), which are involved in extracellular matrix remodeling. Elevated TIMP-1 levels are associated with inflammatory conditions, cancer progression, fibrosis, and joint diseases in dogs. The kit supports studies on disease mechanisms, treatment response monitoring, and biomarker discovery in canine models of cancer, arthritis, and liver or heart disease. It is intended for research use only and not for diagnostic use in clinical practice.