Lexacalcitol is primarily used in the treatment of secondary hyperparathyroidism, a condition often associated with chronic kidney disease. It works by regulating calcium and phosphate metabolism, helping to reduce elevated parathyroid hormone levels. This helps in preventing bone disorders and mineral imbalances in patients undergoing dialysis. Additionally, it is applied in dermatology for managing psoriasis, as it modulates skin cell growth and differentiation, reducing the severity of plaque formation. Its targeted action makes it a valuable therapeutic agent in both renal and dermatological contexts.