Water-dispersible tetrahydrocurcuminoids active complex for brightening, antioxidant and calming skincare; suitable for water-based serums, gels, toners, lotions and creams.
ActiveRelease™ THC (Tetrahydrocurcuminoids Water Dispersible) is a water-dispersible active complex of tetrahydrocurcuminoids for brightening, antioxidant, calming and photoaging-support skincare.
Tetrahydrocurcuminoids are hydrogenated curcuminoids derived from turmeric. Compared with regular yellow curcuminoids, tetrahydrocurcuminoids are much lower in visible color and are better suited to leave-on cosmetics where formulators want turmeric-family activity without strong staining.
This ActiveRelease™ format is designed for water-phase and cool-down processing. It helps formulators use tetrahydrodiferuloylmethane in aqueous serums, gels, toners, lotions and creams where the conventional active would normally require oil/glycol solubilization.
Product Description: The active target is tetrahydrodiferuloylmethane, supported by a water-dispersible carrier system. The key formulation advantage is not that the pure active is water-soluble; rather, this SKU is engineered so the active can be dispersed into water-based systems with less dependence on high glycol or oil-solvent loading.
Skin-benefit evidence for tetrahydrocurcumin/tetrahydrocurcuminoids is strongest in cell and animal models, with supporting mechanistic literature for curcumin-family photoaging pathways. In melanogenesis models, tetrahydrocurcumin has been reported to reduce melanin production and tyrosinase activity, supporting use in uneven-tone and brightening formulas. In a UV-induced photoaging mouse model, tetrahydrocurcumin improved visible wrinkle-related parameters and was associated with extracellular-matrix, inflammation and melanin-biosynthesis pathway changes. Anti-inflammatory data for curcumin metabolites also support NF-κB pathway moderation, which is relevant for redness-prone or stressed-skin positioning.
| Evidence model | Key endpoints | Formulation implication |
|---|---|---|
| Melanoma-cell melanogenesis model | Lower melanin content and tyrosinase activity reported for tetrahydrocurcumin. | Brightening and uneven-tone support. |
| UV-induced photoaging mouse skin | Improved wrinkle/appearance parameters; inflammation, matrix and melanin-pathway changes. | Photoaging-support and antioxidant skincare. |
| Curcumin-metabolite inflammation model | TAK1/NF-κB pathway suppression reported for tetrahydrocurcumin and related metabolites. | Calming support for stressed-looking skin. |
INCI: Cyclodextrin, Tetrahydrodiferuloylmethane.
Usage: Suitable for brightening serums, clear gels, toner/essence products, lotions, creams, masks and antioxidant daytime or nighttime skincare. Pair with sunscreen in daytime brightening routines.
Mixing method:
- Pre-disperse into room-temperature water or a water/glycol phase, then mix until uniform before adding to the main batch.
- Add during cool-down, ideally below 45°C. Avoid prolonged high heat, strong oxidizing systems and unnecessary air entrainment.
- Recommended finished-formula pH: 3.5–7.5. For very low-electrolyte clear gels, confirm clarity and sedimentation after 24–72 hours.
- Protect the finished product from strong light and excessive headspace. Use opaque or airless packaging for formulas positioned around antioxidant performance.
Usage rate: 0.5–2.0%
Use 0.5–2.0% of this active-release complex (delivers approximately 0.1–0.4% tetrahydrodiferuloylmethane). Typical starting point: 1.0% product delivers approximately 0.2% active.
Product characteristics: Light yellow fine powder; characteristic mild odor.
Solubility: Dispersible in water and water/glycol systems. The underlying tetrahydrocurcuminoid active is lipophilic; this product format enables aqueous dispersion.
Storage: Store tightly closed at 15–25°C, protected from light, heat and moisture.
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Water-dispersible tetrahydrocurcuminoids active complex for brightening, antioxidant and calming skincare; suitable for water-based serums, gels, toners, lotions and creams.
ActiveRelease™ THC (Tetrahydrocurcuminoids Water Dispersible) is a water-dispersible active complex of tetrahydrocurcuminoids for brightening, antioxidant, calming and photoaging-support skincare.
Tetrahydrocurcuminoids are hydrogenated curcuminoids derived from turmeric. Compared with regular yellow curcuminoids, tetrahydrocurcuminoids are much lower in visible color and are better suited to leave-on cosmetics where formulators want turmeric-family activity without strong staining.
This ActiveRelease™ format is designed for water-phase and cool-down processing. It helps formulators use tetrahydrodiferuloylmethane in aqueous serums, gels, toners, lotions and creams where the conventional active would normally require oil/glycol solubilization.
Product Description: The active target is tetrahydrodiferuloylmethane, supported by a water-dispersible carrier system. The key formulation advantage is not that the pure active is water-soluble; rather, this SKU is engineered so the active can be dispersed into water-based systems with less dependence on high glycol or oil-solvent loading.
Skin-benefit evidence for tetrahydrocurcumin/tetrahydrocurcuminoids is strongest in cell and animal models, with supporting mechanistic literature for curcumin-family photoaging pathways. In melanogenesis models, tetrahydrocurcumin has been reported to reduce melanin production and tyrosinase activity, supporting use in uneven-tone and brightening formulas. In a UV-induced photoaging mouse model, tetrahydrocurcumin improved visible wrinkle-related parameters and was associated with extracellular-matrix, inflammation and melanin-biosynthesis pathway changes. Anti-inflammatory data for curcumin metabolites also support NF-κB pathway moderation, which is relevant for redness-prone or stressed-skin positioning.
| Evidence model | Key endpoints | Formulation implication |
|---|---|---|
| Melanoma-cell melanogenesis model | Lower melanin content and tyrosinase activity reported for tetrahydrocurcumin. | Brightening and uneven-tone support. |
| UV-induced photoaging mouse skin | Improved wrinkle/appearance parameters; inflammation, matrix and melanin-pathway changes. | Photoaging-support and antioxidant skincare. |
| Curcumin-metabolite inflammation model | TAK1/NF-κB pathway suppression reported for tetrahydrocurcumin and related metabolites. | Calming support for stressed-looking skin. |
INCI: Cyclodextrin, Tetrahydrodiferuloylmethane.
Usage: Suitable for brightening serums, clear gels, toner/essence products, lotions, creams, masks and antioxidant daytime or nighttime skincare. Pair with sunscreen in daytime brightening routines.
Mixing method:
- Pre-disperse into room-temperature water or a water/glycol phase, then mix until uniform before adding to the main batch.
- Add during cool-down, ideally below 45°C. Avoid prolonged high heat, strong oxidizing systems and unnecessary air entrainment.
- Recommended finished-formula pH: 3.5–7.5. For very low-electrolyte clear gels, confirm clarity and sedimentation after 24–72 hours.
- Protect the finished product from strong light and excessive headspace. Use opaque or airless packaging for formulas positioned around antioxidant performance.
Usage rate: 0.5–2.0%
Use 0.5–2.0% of this active-release complex (delivers approximately 0.1–0.4% tetrahydrodiferuloylmethane). Typical starting point: 1.0% product delivers approximately 0.2% active.
Product characteristics: Light yellow fine powder; characteristic mild odor.
Solubility: Dispersible in water and water/glycol systems. The underlying tetrahydrocurcuminoid active is lipophilic; this product format enables aqueous dispersion.
Storage: Store tightly closed at 15–25°C, protected from light, heat and moisture.
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