Used as a key reagent in organic synthesis, particularly in the formation of ketones through the Weinreb–Nahm amide pathway. It reacts with organometallic reagents like Grignard or organolithium compounds to provide controlled addition products without over-addition, making it ideal for constructing complex molecules in pharmaceutical and natural product synthesis. Its stability and selectivity enhance efficiency in multi-step reactions, especially in the development of active pharmaceutical ingredients (APIs). Commonly employed in research laboratories and industrial settings for carbonyl elongation and functional group transformations.