Used as a catalyst in asymmetric synthesis, particularly in enantioselective transformations where chiral control is critical. Its zinc center coordinated with a chiral ligand framework enables efficient induction of stereochemistry in carbon–carbon bond-forming reactions. Commonly applied in the synthesis of biologically active molecules, including pharmaceutical intermediates, where high enantiomeric excess is required. Also explored in coordination chemistry for designing metalloenzyme mimics due to its stable chiral environment and moderate Lewis acidity.