2-(4-Bromo-2-fluorophenyl)-1,3-dioxolane
≥95%
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description Product Description
2-(4-Bromo-2-fluorophenyl)-1,3-dioxolane serves as a protected form of 4-bromo-2-fluorobenzaldehyde and is used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of fluorinated active pharmaceutical ingredients (APIs). Its structure enables selective functionalization, with the dioxolane group protecting the aldehyde while allowing reactions at the aryl bromide. This makes it valuable in medicinal chemistry for constructing complex molecules with improved metabolic stability and binding affinity. It is commonly employed in cross-coupling reactions to incorporate the bromo-fluorophenyl moiety into larger drug-like structures. Additionally, it is utilized in research for preparing novel bioactive molecules and fluorinated analogs in drug discovery programs.
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