Spirendolol is primarily used in pharmacological research as a beta-adrenergic receptor antagonist. It is often employed in studies to investigate the effects of beta-blockade on various physiological processes, particularly in the cardiovascular system. Researchers utilize spirendolol to understand its potential therapeutic benefits in managing conditions like hypertension, arrhythmias, and other heart-related disorders. Its application extends to experimental models where it helps in elucidating the role of beta-adrenergic receptors in stress responses and cardiac function. Additionally, spirendolol is sometimes used in comparative studies to evaluate the efficacy and selectivity of newer beta-blockers.