3-(3,4-Difluorophenyl)propiolic acid
95%
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description Product Description
Used in organic synthesis as a building block for pharmaceuticals and agrochemicals, particularly in the development of fluorinated compounds with enhanced biological activity. Its alkyne and carboxylic acid functional groups allow for participation in coupling reactions, such as Sonogashira or click chemistry, enabling the construction of complex molecular architectures. Commonly employed in medicinal chemistry for structure-activity relationship studies due to the electron-withdrawing effect and metabolic stability imparted by the difluorophenyl group. Also utilized in the synthesis of kinase inhibitors and other bioactive molecules where fluorine substitution improves target selectivity and pharmacokinetic properties.
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