“Closest direct evidence: a topical amino-acid combination containing DL-threonine, L-cysteine and glycine showed improved healing and pain reduction in hypostatic leg ulcers versus placebo.”
L-Threonine
Cosmetics
Code: 6046
L-Threonine
L-Threonine
Usage: For any product
Mixing method: Mix in water
Rate of use: 0.1-1%
Product characteristics: White powder, light color
Solubility: Can dissolve in water (Please check the dissolution level)
INCI Name : L-Threonine
- Room (25-40C)
- 24 Months from manufacturing or testing date.
- 0.10% - 1.00%
- 0.00%
- Add into water phase. Avoid temperature above 60C.
- Avoid heat above 60C
- 0.00 - 0.00
- Soluble in Water
- -
| Test Name | Specification |
|---|---|
| Assay | 98.5-101.5% |
| Specific Rotation | -26.7 to -29.0 |
| Chloride | 0.05% Max |
| Sulfate | 0.03% Max |
| Heavy Metals | 15ppm Max |
| Arsenic | 1.5ppm Max |
| Iron | 0.03% Max |
| Residue on Ignition | 0.1% Max |
| Loss on drying | 0.2% Max |
| pH Value | 5.0-6.5 |
“Closest direct evidence: L-cysteine, glycine and DL-threonine were evaluated in randomized wound-healing models on human forearm blister bases and hypostatic leg ulcers.”
“Ingredient-family evidence: natural moisturizing factor contains hygroscopic amino acids, supporting stratum corneum hydration and barrier-related skin benefits; applicable to threonine as an amino-acid NMF component rather than as isolated L-threonine proof.”
“Ingredient-family evidence: NMF components in stratum corneum are measurable biomarkers linked to filaggrin status and skin barrier/hydration biology; supports amino-acid moisturization rationale rather than isolated L-threonine efficacy.”
“Ingredient-family evidence: topical amino-acid dressing improved cutaneous wound healing in aged rats, supporting amino-acid mixtures for skin repair, but not proving isolated L-threonine benefit.”
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