“Direct clinical evidence: L-phenylalanine combined with UVA supported repigmentation benefit in vitiligo patients, but this is a medical phototherapy context, not ordinary cosmetic moisturization.”
L-Phenylalanine
Cosmetics
Code: 6197
L-Phenylalanine
L-Phenylalanine
Usage: For any product
Mixing method: Mix in water
Rate of use: 0.1-1%
Product characteristics: White powder, light color
Solubility: Can dissolve in water (Please check the dissolution level)
INCI Name : L-Phenylalanine
- Room (25-40C)
- 24 Months from manufacturing or testing date.
- 0.10% - 1.00%
- 0.00%
- Add into water phase. Avoid temperature above 60C.
- Avoid heat above 60C
- 0.00 - 0.00
- Soluble in Water
- -
| Test Name | Specification |
|---|---|
| Appearance | white crystalline powder |
| Specific rotation | -32.7° to -34.7° |
| Content, % | 98.5–101.5 |
| Loss on drying, % | ≤0.30 |
| Heavy metals, % | ≤0.0015 |
| Residue on ignition, % | ≤0.40 |
| Iron | ≤0.003% |
| pH | 5.4–6.0 |
| Chloride | ≤0.05 |
| Sulfate (SO4) | ≤0.03 |
| Other amino acids | Complies |
“Direct clinical evidence: oral and topical phenylalanine with UVA exposure was reported effective for vitiligo repigmentation in a small patient study.”
“Direct clinical evidence: L-phenylalanine plus UVA showed positive repigmentation responses in vitiligo, including an open trial and a small double-blind trial.”
“Direct clinical evidence: oral and topical L-phenylalanine with clobetasol and UVA/sunlight improved evolutive vitiligo; evidence is disease-treatment focused, not general cosmetic skin brightening.”
“Closest ingredient-family evidence: free amino acids in stratum corneum act as natural moisturizing factors, supporting hydration/barrier relevance for amino acids generally rather than L-phenylalanine alone.”
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