Tobramycin sulfate is widely used in the treatment of bacterial infections, particularly those caused by Gram-negative bacteria. It is commonly applied in the management of respiratory infections, such as those occurring in patients with cystic fibrosis, where it helps reduce bacterial load in the lungs. The compound is also utilized in ophthalmic solutions to treat eye infections like conjunctivitis and keratitis. Additionally, it is employed in topical formulations for skin infections and in intravenous or intramuscular injections for severe systemic infections. Its effectiveness against Pseudomonas aeruginosa makes it a critical component in combating infections in immunocompromised patients.