4-(1H-Tetrazol-5-yl)benzoic Acid
97%
Reagent
Code: #172668
CAS Number
34114-12-0
blur_circular Chemical Specifications
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Molecular Information
Weight
190.16 g/mol
Formula
C₈H₆N₄O₂
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Registry Numbers
MDL Number
MFCD06345720
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, such as valsartan, irbesartan, and losartan—medications widely prescribed for hypertension and heart failure. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing metabolic stability and receptor binding affinity. Also employed in coordination chemistry as a ligand for metal-organic frameworks (MOFs) due to its ability to chelate metal ions. Additionally, finds use in medicinal chemistry for developing new bioactive compounds with potential anti-inflammatory or anticancer properties.
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