Humulone is primarily known for its role in the brewing industry, where it serves as a key component in the bitterness and flavor profile of beer. Derived from hops, it is one of the primary alpha acids that undergo isomerization during the brewing process, contributing to the characteristic bitter taste of beer. Beyond brewing, humulone has been studied for its potential health benefits, including anti-inflammatory, antimicrobial, and anticancer properties. Research suggests it may help inhibit the growth of certain bacteria and viruses, making it a subject of interest in pharmaceutical and nutraceutical applications. Additionally, its antioxidant properties are being explored for use in dietary supplements and functional foods aimed at promoting overall health and wellness.