Xanthoangelol is a natural chalcone compound isolated from the plant Angelica keiskei. It is primarily studied for its potential therapeutic applications due to its bioactive properties. It exhibits significant anti-inflammatory effects, making it a candidate for developing treatments for inflammatory diseases, including skin inflammation. Additionally, its antioxidant properties are being explored for combating oxidative stress-related conditions, such as neurodegenerative disorders and aging. Research also highlights its potential anticancer activity, as it has been shown to inhibit the growth of certain cancer cells. Furthermore, xanthoangelol is being investigated for its role in metabolic regulation, particularly in managing diabetes and obesity. Its ability to modulate various cellular pathways underscores its versatility in medical research and drug development, with potential applications in nutraceuticals and cosmetics.