Piperine is widely used in the food industry as a natural flavor enhancer, particularly in spicy dishes, due to its pungent and sharp taste. It is a key component in black pepper, contributing to its characteristic flavor. In the pharmaceutical sector, piperine is utilized as a bioenhancer to improve the absorption and efficacy of various drugs, including antibiotics, antivirals, and anticancer medications. Its ability to increase bioavailability makes it valuable in drug formulations. Additionally, piperine is incorporated into dietary supplements for its potential health benefits, such as antioxidant, anti-inflammatory, and metabolism-boosting properties. It is also studied for its role in enhancing nutrient absorption, particularly in the case of curcumin, improving its therapeutic effects. In traditional medicine, piperine is used to treat digestive issues, improve appetite, and alleviate pain. Its applications extend to cosmetics, where it is included in skincare products for its potential anti-aging and skin-brightening effects.