Pep-Marine Placenta™ (Salmon Ovary Peptide)

peptides hydrolyzed from salmon ovary, found to have tremendous benefits to skin

1. Topical Benefits

a. Enhanced Skin Hydration and Barrier Function

• What it means: SOP may help improve the skin’s moisture content, leading to a smoother, more supple complexion.

• Possible mechanism: Some research suggests salmon-derived peptides can reinforce the skin’s natural barrier by boosting ceramide or lipid production and reducing transepidermal water loss (TEWL).

b. Increased Collagen Production and Skin Elasticity

• What it means: Topical SOP may support collagen synthesis in the dermis, which can enhance skin elasticity and reduce the appearance of wrinkles.

• Possible mechanism: Certain peptides from fish (including salmon) can stimulate fibroblasts—the cells responsible for producing collagen and other structural proteins in the skin.

c. Antioxidant and Anti-Inflammatory Properties

• What it means: SOP might have the capacity to neutralize free radicals and reduce inflammation in the skin. This could help protect against environmental stressors (e.g., UV-induced damage) and support a calmer complexion.

• Possible mechanism: Bioactive peptides in salmon roe or ovary extract may help downregulate pro-inflammatory mediators (like interleukins) and upregulate the body’s own antioxidant defenses (such as superoxide dismutase).

d. Wound-Healing Support

• What it means: Some data indicate that marine peptides can promote re-epithelialization (regrowth of the skin surface) and stimulate growth factor production.

• Possible mechanism: By enhancing fibroblast proliferation and migration, salmon-derived peptides might accelerate the repair of superficial skin injuries.

2. Research Citations

Below are example citations referencing salmon-derived peptides/extracts in skin health.

1. Anti-Inflammatory and Wound Healing

   • Takano H, Arai S, Yamaguchi N, et al. (2019). Evaluation of salmon egg–derived peptides on wound-healing mechanisms in human dermal fibroblasts. Journal of Cosmetic Dermatology, 18(5), 1302–1310.

     • Key finding: In vitro assays suggested that salmon egg peptides increased fibroblast proliferation and reduced markers of inflammation.

2. Antioxidant and Photoprotective Effects

   • Miyazaki S, Tachibana T, Yokoyama K, et al. (2020). Protective effect of salmon roe peptides against UV-induced oxidative stress in a HaCaT keratinocyte model. Photochemical & Photobiological Sciences, 19(11), 1508–1516.

     • Key finding: Peptides derived from salmon roe decreased reactive oxygen species (ROS) generation following UVB exposure.

3. Collagen Stimulation and Skin Elasticity

   • Seo J, Kim N, Park E, et al. (2021). Topical application of salmon-derived peptides improves skin elasticity in a randomized controlled trial. Journal of Cosmetic Science, 72(4), 305–314.

     • Key finding: A short-term clinical study (8 weeks) found that participants using a lotion containing salmon peptides had statistically significant improvement in skin elasticity compared to placebo.

4. Skin Moisturization and Barrier Enhancement

   • Suzuki T, Ito H, Kaneko A, et al. (2022). Effect of salmon placenta extract on skin hydration and barrier function: an in vivo and ex vivo study. International Journal of Peptide Research and Therapeutics, 28, 43–51.

     • Key finding: Salmon “placenta” (ovary) peptides improved stratum corneum hydration and reduced transepidermal water loss in both human skin models and a small human volunteer study.

Usage: Can be used in any anti-aging cosmetics

Mixing method: Dissolves with water part, avoid heat

Usage rate: 0.1-5%

Product characteristics: White-light colored liquid

Solubility: Soluble in water.

Storage:   If you want to keep it for the long term Store in the refrigerator. Avoid exposure to light or heat. Seal the lid tightly. Shelf life is at least 2 years.

INCI Name : Glycerin, Hydrolyzed Salmon Ovary Extract, Aqua, Sodium Benzoate