(Z)-5-(4-Hydroxybenzylidene)-3-isobutyl-2-thioxothiazolidin-4-one
98%
Reagent
Code: #246709
CAS Number
1558598-41-6
science Other reagents with same CAS 1558598-41-6
blur_circular Chemical Specifications
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Molecular Information
Weight
293.4044 g/mol
Formula
C₁₄H₁₅NO₂S₂
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Registry Numbers
MDL Number
MFCD02220972
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Storage & Handling
Storage
2-8°C
description Product Description
Used in the development of antidiabetic agents due to its structural similarity to thiazolidinediones, a class of insulin sensitizers. It serves as a key intermediate in synthesizing compounds that target peroxisome proliferator-activated receptor gamma (PPARγ), helping regulate glucose metabolism and fatty acid storage. Its (Z)-configuration enhances binding affinity to PPARγ, improving efficacy in lowering blood glucose levels in preclinical studies. Also investigated for anti-inflammatory and antioxidant properties, supporting potential use in treating metabolic syndrome and type 2 diabetes complications.
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