(Z)-5-(4-Hydroxybenzylidene)-3-isobutyl-2-thioxothiazolidin-4-one

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Reagent Code: #246709
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CAS Number 1558598-41-6

science Other reagents with same CAS 1558598-41-6

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Weight 293.4044 g/mol
Formula C₁₄H₁₅NO₂S₂
badge Registry Numbers
MDL Number MFCD02220972
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used in the development of antidiabetic agents due to its structural similarity to thiazolidinediones, a class of insulin sensitizers. It serves as a key intermediate in synthesizing compounds that target peroxisome proliferator-activated receptor gamma (PPARγ), helping regulate glucose metabolism and fatty acid storage. Its (Z)-configuration enhances binding affinity to PPARγ, improving efficacy in lowering blood glucose levels in preclinical studies. Also investigated for anti-inflammatory and antioxidant properties, supporting potential use in treating metabolic syndrome and type 2 diabetes complications.

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Size Availability Unit Price Quantity
inventory 25mg
10-20 days ฿4,920.00
inventory 100mg
10-20 days ฿8,310.00

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(Z)-5-(4-Hydroxybenzylidene)-3-isobutyl-2-thioxothiazolidin-4-one
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Used in the development of antidiabetic agents due to its structural similarity to thiazolidinediones, a class of insulin sensitizers. It serves as a key intermediate in synthesizing compounds that target peroxisome proliferator-activated receptor gamma (PPARγ), helping regulate glucose metabolism and fatty acid storage. Its (Z)-configuration enhances binding affinity to PPARγ, improving efficacy in lowering blood glucose levels in preclinical studies. Also investigated for anti-inflammatory and antioxidant properties, supporting potential use in treating metabolic syndrome and type 2 diabetes complications.
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