2-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)pyridine

95%

Reagent Code: #129802
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CAS Number 2792143-50-9

science Other reagents with same CAS 2792143-50-9

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 307.5 g/mol
Formula C₁₂H₁₄BClF₃NO₂
badge Registry Numbers
MDL Number MFCD13182153
thermostat Physical Properties
Boiling Point 344.3±42.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.27±0.1 g/cm3(Predicted)
Storage 2-8°C, Sealed, Inert Gas

description Product Description

Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions to synthesize pharmaceuticals and agrochemicals. Its boronate ester group enables efficient carbon-carbon bond formation, particularly in the development of trifluoromethyl-substituted pyridine derivatives, which are common motifs in bioactive molecules. Widely applied in medicinal chemistry for constructing drug candidates targeting central nervous system disorders, inflammation, and metabolic diseases. Also employed in the preparation of advanced intermediates for crop protection agents due to the stability and lipophilicity imparted by the trifluoromethyl group.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿2,550.00
inventory 250mg
10-20 days ฿4,450.00

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2-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)pyridine
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Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions to synthesize pharmaceuticals and agrochemicals. Its boronate ester group enables efficient carbon-carbon bond formation, particularly in the development of trifluoromethyl-substituted pyridine derivatives, which are common motifs in bioactive molecules. Widely applied in medicinal chemistry for constructing drug candidates targeting central nervous system disorders, inflammation, and metabolic diseases. Also employed in the preparatio

Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions to synthesize pharmaceuticals and agrochemicals. Its boronate ester group enables efficient carbon-carbon bond formation, particularly in the development of trifluoromethyl-substituted pyridine derivatives, which are common motifs in bioactive molecules. Widely applied in medicinal chemistry for constructing drug candidates targeting central nervous system disorders, inflammation, and metabolic diseases. Also employed in the preparation of advanced intermediates for crop protection agents due to the stability and lipophilicity imparted by the trifluoromethyl group.

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