2-(3-Chloro-5-(cyclopropylmethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
98%
Reagent
Code: #164551
CAS Number
1218789-44-6
blur_circular Chemical Specifications
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Molecular Information
Weight
308.61 g/mol
Formula
C₁₆H₂₂BClO₃
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Registry Numbers
MDL Number
MFCD12546580
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in the synthesis of complex organic molecules. Particularly valuable in pharmaceutical development for constructing biaryl systems, where the boronate ester group facilitates coupling with aryl halides under mild conditions. Its cyclopropylmethoxy and chloro-substituted phenyl structure allows for selective modifications in drug candidates, improving metabolic stability and target binding. Commonly employed in late-stage functionalization due to its compatibility with various functional groups and high coupling efficiency.
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