MI-2

≥98%

Reagent Code: #101386
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CAS Number 1271738-62-5

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 375.55 g/mol
Formula C₁₈H₂₅N₅S₂
inventory_2 Storage & Handling
Storage  -20°C

description Product Description

MI-2 is primarily utilized in research settings to study its interaction with the NOTCH signaling pathway, which plays a crucial role in cellular differentiation, proliferation, and apoptosis. It is particularly investigated for its potential to inhibit the activity of the MAML1 protein, a key coactivator in the NOTCH pathway. This inhibition is of significant interest in cancer research, as aberrant NOTCH signaling is implicated in various malignancies. By targeting this pathway, MI-2 serves as a tool to explore therapeutic strategies for cancers where NOTCH signaling is dysregulated, such as T-cell acute lymphoblastic leukemia (T-ALL) and other NOTCH-dependent tumors. Additionally, it aids in understanding the broader biological mechanisms influenced by NOTCH signaling in both normal and pathological conditions.

format_list_bulleted Product Specification

Test Parameter Specification
Appearance Yellow Solid
Purity (%) 98-100
NMR Consistent with Structure
Infrared Spectrum Conforms To Structure

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 25mg
10-20 days ฿32,436.00
inventory 5mg
10-20 days ฿8,982.00
inventory 100mg
10-20 days ฿64,881.00
MI-2
MI-2 is primarily utilized in research settings to study its interaction with the NOTCH signaling pathway, which plays a crucial role in cellular differentiation, proliferation, and apoptosis. It is particularly investigated for its potential to inhibit the activity of the MAML1 protein, a key coactivator in the NOTCH pathway. This inhibition is of significant interest in cancer research, as aberrant NOTCH signaling is implicated in various malignancies. By targeting this pathway, MI-2 serves as a tool to explore therapeutic strategies for cancers where NOTCH signaling is dysregulated, such as T-cell acute lymphoblastic leukemia (T-ALL) and other NOTCH-dependent tumors. Additionally, it aids in understanding the broader biological mechanisms influenced by NOTCH signaling in both normal and pathological conditions.
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