L-(-)-Fucose is widely used in biochemical and biomedical research, particularly in studies related to cell signaling and immune responses. It serves as a key building block in the synthesis of complex carbohydrates found on the surface of cells, especially in glycoproteins and glycolipids. These fucose-containing structures play critical roles in cell-cell recognition, inflammation, and pathogen attachment. It is also applied in the development of therapeutic agents, including anti-inflammatory drugs and cancer vaccines, due to its involvement in tumor-associated carbohydrate antigens. In biotechnology, L-(-)-Fucose is used to engineer glycosylated antibodies with enhanced efficacy, as fucosylation affects antibody-dependent cellular cytotoxicity (ADCC). Additionally, it supports the production of human milk oligosaccharides in infant formula research, aiming to improve gut health and immunity in newborns.