Anacetrapib

≥99%

Reagent Code: #77453
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CAS Number 875446-37-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 637.51 g/mol
Formula C₃₀H₂₅F₁₀NO₃
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Anacetrapib was investigated for its potential in cardiovascular disease management but development was discontinued in 2017 by Merck following the REVEAL trial, which showed modest efficacy but raised concerns about long-term safety and off-target effects. It functions as a cholesteryl ester transfer protein (CETP) inhibitor, which helps in increasing high-density lipoprotein (HDL) cholesterol levels while reducing low-density lipoprotein (LDL) cholesterol. This dual action made it a candidate for reducing the risk of heart attacks and strokes in patients with a history of cardiovascular issues. Clinical trials explored its efficacy in combination with statins to enhance cholesterol management. It is not approved for clinical use and is available primarily as a research chemical.

format_list_bulleted Product Specification

Test Parameter Specification
Appearance White to off-white solid
Purity 98.5-100
Infrared Spectrum Conforms to Structure
NMR Conforms to Structure

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿98,800.00
inventory 5mg
10-20 days ฿9,190.00
inventory 10mg
10-20 days ฿15,960.00
inventory 50mg
10-20 days ฿53,980.00

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