Sepharose® CL-2B is widely used in biochemical and biotechnological applications for the separation and purification of biomolecules. Its cross-linked structure provides enhanced stability, making it suitable for use in various chromatographic techniques. It is particularly effective in gel filtration chromatography, where it separates molecules based on size. This makes it ideal for purifying large biomolecules such as proteins, nucleic acids, and polysaccharides. Additionally, it is used in the preparation of affinity chromatography media by coupling specific ligands to its matrix for targeted purification. Its applications extend to the study of molecular interactions and the isolation of cell organelles or macromolecular complexes. The high porosity and mechanical strength of Sepharose® CL-2B make it a reliable choice for both research and industrial-scale processes.