Melagatran is primarily used as an anticoagulant to prevent and treat blood clots. It is effective in reducing the risk of stroke in patients with atrial fibrillation, a condition characterized by irregular heartbeats. Additionally, it is utilized in the prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE) in patients undergoing certain types of surgery. Melagatran works by inhibiting thrombin, a key enzyme in the blood clotting process, thereby preventing the formation of clots. Its application is particularly beneficial for patients who require rapid and reversible anticoagulation.