1-Oleoyl-2-acetyl-sn-glycerol (OAG) is widely used in biochemical and pharmacological research as a potent activator of protein kinase C (PKC). It serves as a valuable tool in studying PKC signaling pathways, which are crucial for understanding cellular processes such as proliferation, differentiation, and apoptosis. OAG is particularly useful in mimicking the effects of diacylglycerol (DAG), a natural second messenger, making it essential for experiments exploring cell signaling mechanisms. Additionally, it is employed in studies related to immune response, cancer research, and neuronal function, providing insights into the role of PKC in various physiological and pathological conditions. Its ability to penetrate cell membranes efficiently makes it a preferred choice for in vitro and ex vivo studies.